The production levels for the half dollar saw a surprising jump to start the new decade and millennium. These levels were roughly double the mintages seen in the previous year.
In general, circulating coin production figures were much higher at the United States Mint driven by a robust economy and renewed interest in collector spurred by the 50 State Quarters Program. More people were paying attention to their pocket change and saving coins from circulation rather than spending them. Although the half dollars were rarely seen in circulation at this point, some banks could still provide original wrapped rolls.
The mintages for the 2000-S Proof Kennedy Half Dollars rose for both the clad composition and 90% silver composition coins.
Mintage:
| Philadelphia | Denver | Proof | Silver Proof |
| 22,600,000 | 19,466,000 | 3,082,483 | 965,421 |